金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FRA-1 Long Name: Fos-related antigen 1 Aliases: FOSL1 Entrez Gene IDs: 8061 (Human); 14283 (Mouse); 25445 (Rat) Background: Fos/Jun Family The AP-1 transcription factor is mainly composed of Jun (c-Jun, JunB, JunD), Fos (c-Fos, FosB, Fra-1, Fra-2) and ATF (ATFa, ATF-2, ATF-3) protein dimers. All contain the bZIP basic DNA-binding leucine zipper domain. Jun, but not Fos, proteins can homodimerize. AP-1 mediates gene regulation in response to cytokines, growth factors, stress signals, bacterial and viral infections, oncogenic stimuli and other physiological and pathological stimuli.