金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Carboxylesterase 1/CES1 Aliases: ACAT; CES1; Egasyn; HMSE1; REH; SES1; TGH Entrez Gene IDs: 1066 (Human); 12623 (Mouse); 29225 (Rat) Background: Carboxylesterase 1 Carboxylesterase 1 hydrolyzes ester- and amide bonds of substrates ranging from small molecule esters such as phenylester to long-chain fatty acid esters and thioesters. It plays a major role in the pharmacokinetic behavior of many therapeutic agents containing an ester. Through de-esterification, it participates in the detoxification of drugs such as cocaine and heroin in serum and liver.