金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Neurexophilin-1 Aliases: NPH1; NXPH1 Entrez Gene IDs: 30010 (Human); 18231 (Mouse); 25501 (Rat) Background: Neurexophilin Family Neurexophilins (NXPH) are a family of neuropeptide-like secreted glycoproteins expressed in specific regions of the brain. NXPH1 is expressed mainly by cells that resemble inhibitory interneurons, while NXPH3 is found selectively in subplate-derived neurons in cortical layer 6b, granule cells in the vestibulocerebellum and Cajal-Retzius cells during development. NXPH1, 2 and 3 are tightly bound extracellular ligands of alpha-neurexins, synaptic transmembrane molecules that are essential for calcium-triggered neurotransmitter release. NXPH2 is not expressed in rodents, and NXPH4 does not bind alpha-neurexins.