金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: NETO2 Long Name: Neuropilin [NRP] And Tolloid [TLL]-like 2 Aliases: BTCL2; NEOT2 Entrez Gene IDs: 81831 (Human); 74513 (Mouse); 307757 (Rat) Background: NETO2 NETO2 is a neurospecific type I transmembrane protein belonging to the NETO family of proteins that share homology with the axon guidance receptors, neuropilin and the developmentally important metalloproteinase Tolloid/BMP-1. NETO proteins have two CUB domains, an LDL-receptor class A domain in their extracellular region and a conserved FXNPXY-like domain in the cytoplasmic region. A splice variant of NETO2 that lacks the CUB domains and most of the LDL class A domain has been reported. It is likely that like NETO1, NETO2 may be a synaptic protein with neurological function. Human and mouse NETO2 share 98% amino acid sequence homology in their extracellular domains.