金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Bub1 Long Name: BUB1 Budding Uninhibited By Benzimidazoles 1 Homolog Entrez Gene IDs: 699 (Human); 12235 (Mouse) Background: Bub1 The Bub1 protein is a serine/threonine kinase that acts in the mitotic spindle checkpoint by recruiting components and promoting kinetochore formation in the inner centromere. Bub1 delays chromosome segregation in response to genotoxic stress. Mutations or the absence of Bub1 can lead to aneuploidy, chromosomal instability, and premature senescence.