金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TAB1 Long Name: TAK1-binding Protein Aliases: MAP3K7IP1 Entrez Gene IDs: 10454 (Human); 66513 (Mouse); 315139 (Rat) Background: TAB1 TAB1 is a 55 kDa scaffold protein that is involved a number of cytokine signaling pathways. It binds to TAK1 (MAPK kinase kinase 7), a downstream signaling molecule associated with both TGF-beta and inflammatory cytokine activity. TAB1 interaction with TAK1 promotes TAK1 autophosphorylation. It also has TAK1-independent signaling activity that involves TGF-beta and p38