金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: HES-1 Long Name: Hairy And Enhancer of Split 1 Aliases: HL; HRY Entrez Gene IDs: 3280 (Human); 15205 (Mouse); 29577 (Rat) Background: HES-1 HES-1 is a member of the basic helix-loop-helix O (bHLH-O) family of nuclear transcriptional repressors that function in maintaining the undifferentiated state of progenitor cells. HES-1 contains a bHLH DNA binding domain that can be blocked by serine phosphorylation, an orange domain required for homodimer and heterodimer formation, a proline-rich domain, a serine/threonine rich domain, and a WRPW motif for interaction with the Groucho co-repressor.