金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Lyn Long Name: V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog Aliases: Hck-2; JTK8; v-yes-1 Entrez Gene IDs: 4067 (Human); 17096 (Mouse); 81515 (Rat) Background: Lyn The nonreceptor tyrosine kinase Lyn (lck/yes-related novel tyrosine kinase) is widely expressed, and the predominant Src family member present in B cells. Activation of Lyn occurs upon its association with cell surface receptors such as BCR and CD40. Analyses from both loss- and gain-of-function mutant mice have revealed that Lyn is an essential regulator of B cell activation, maturation, and tolerance.