金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IL-1ra/IL-1F3 Long Name: Interleukin 1 Receptor Antagonist Aliases: IL-1F3; IL1RN Entrez Gene IDs: 3557 (Human); 16181 (Mouse); 60582 (Rat); 397499 (Porcine) Background: IL-1ra/IL-1F3 IL-1 receptor antagonist (IL-1ra) was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1RII does not bind IL-1ra.