金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SDNSF/MCFD2 Long Name: Stem Cell-derived Neuronal Stem/Progenitor Cell Supporting Factor Aliases: MCFD2 Entrez Gene IDs: 90411 (Human); 193813 (Mouse) Background: SDNSF/MCFD2 SDNSF (stem cell-derived neural stem/progenitor cell supporting factor ), also known as MCFD2 (multiple coagulation factor deficiency 2), was described as a secreted molecule from adult hippocampal neural stem/progenitor cells (ANSC). SDNSF functions as an autocrine/paracrine factor to maintain neurogenesis in the central nervous system. It is a component of the MCDF2-LMAN1 complex that functions as a specific cargo receptor for the ER to Golgi transport of proteins. Mutations in MCFD2 causes factor 5 and factor 8 combined deficiency.