货号：14-664M

品牌：Merck Millipore

规格：

目录价：￥30125.00

市场价格：￥25606.25

会员价格：￥24100.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Mnk2, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human, full length Mnk2 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: Q9HBH9 # May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.COFACTOR: Magnesium. & Binds 1 zinc ion per subunit.SIZE: 465 amino acids; 51875 Da SUBUNIT: Monomer. Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2. Isoform 2 interacts with ESR2.TISSUE SPECIFICITY: Ubiquitously expressed in all tissues examined. Isoform 2 is expressed at higher levels in the ovary than is isoform 1.PTM: Dual phosphorylation of Thr-244 and Thr-249 activates the kinase. Phosphorylation of Thr-379 activates the kinase.SIMILARITY: SwissProt: Q9HBH9 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 50kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 cells View All» Protein Target: Mnk2 View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: CAMK View All» Gene Symbol:

• MKNK2

• GPRK7

• Mnk2

• MNK2
  View All» Product Name: Mnk2, active View All» Quality Assurance: routinely evaluated by phosphorylation of MBP (Catalog # 13-104) View All» UniProt Number: Q9HBH9 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-664) and in bulk (cat# 14-664-K). View All» Entrez Gene Number:
  • NM_017572.3

  • NM_199054.2
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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