货号:14-658M
品牌:Merck Millipore
规格:250Ug
目录价:¥42566.00
市场价格:¥36181.10
会员价格:¥34052.80
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Description:
WNK3, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
250 µg
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Product Overview:
N-terminal 6His-tagged, recombinant, human WNK3, amino acids 1-434
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]
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UniProt Summary:
COFACTOR: Magnesium (By similarity).SIZE: 1743 amino acids; 191789 Da TISSUE SPECIFICITY: Expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney. Very low levels of expression were also detected in fetal heart, thymus, liver and spleen.SIMILARITY: SwissProt: Q9BYP7 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. & Contains 1 protein kinase domain.
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Species:
Human
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Molecular Weight:
53.1kDa
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Brand Family:
Upstate
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Source:
Expressed by baculovirus in Sf21 cells
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Protein Target:
WNK3
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Storage Conditions:
6 months at -70°C
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Target Sub-Family:
STE
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Gene Symbol:
-
WNK3
-
KIAA1566
-
PRKWNK3
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Product Name:
WNK3, active
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Quality Assurance:
Routinely evaluated by phosphorylation of MBP (#13-104).
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UniProt Number:
Q9BYP7
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
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Packaging:
Also available in 10 μg size (cat#14-658) and in bulk (cat# 14-658-K).
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Entrez Gene Number:
-
NM_001002838.1
-
NM_020922.2
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Purification Method:
Ni2+/NTA-agarose
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