货号：14-652M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: SIK, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human SIK, amino acids 1-281. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: P57059 # Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3 (By similarity).COFACTOR: Magnesium.SIZE: 783 amino acids; 84902 Da SUBUNIT: Binds to and is activated by YWHAZ when phosphorylated on Thr-182.SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: P57059 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. & Contains 1 protein kinase domain. & Contains 1 UBA domain. View All» Species: Human View All» Molecular Weight: 36.2kDa View All» Brand Family: Upstate View All» Source: Expressed by baculovirus in Sf21 insect cells. View All» Protein Target: SIK View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment View All» Target Sub-Family: CAMK View All» Gene Symbol:

• SNF1LK

• MSK

• msk

• SIK

• SIK1
  View All» Product Name: SIK, active View All» Quality Assurance: Routinely evaluated by phosphorylation of AMARA Substrate Peptide (Catalog# 12-557). View All» UniProt Number: P57059 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-652) and in bulk (cat# 14-652-K). View All» Entrez Gene Number: NM_173354.3 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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  © Merck Millipore代理14-652M SIK Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio