货号：14-604M

品牌：Merck Millipore

规格：1EA

目录价：￥38599.60

市场价格：￥32809.66

会员价格：￥30879.68

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PI3 Kinase (p110δ/p85α), active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: Complex of N-terminal His6-tagged recombinant, full-length, human p110δ and untagged, recombinant, full length, human p85α View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha (MIM 171834), p110-beta (MIM 602925), and p110-gamma (MIM 601232). p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins (see MIM 171833) and with GTP-bound Ras.[supplied by OMIM] View All» UniProt Summary: SIZE: 1044 amino acids; 119479 Da SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Interacts with ERAS (By similarity).TISSUE SPECIFICITY: Expressed predominantly in leukocytes.PTM: Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.SIMILARITY: SwissProt: O00329 ## Belongs to the PI3/PI4-kinase family. & Contains 1 PI3K/PI4K domain. View All» Species: Human View All» Molecular Weight: P110δ (121.6kDa) & p85α (83.7kDa) View All» Brand Family: Upstate View All» Source: Coexpressed by baculovirus in Sf21 insect cells View All» Protein Target: PI3Kδ/p85α View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: PI3K/PI4K View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• PIK3CD

• p110d

• PI3K

• p110D

• p110delta
  View All» Product Name: PI3 Kinase (p110δ/p85α), active View All» Quality Assurance: routinely evaluated by the PIProfiler™ View All» UniProt Number: O00329 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-604) and in bulk (cat# 14-604-K). View All» Entrez Gene Number: NM_005026.2 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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