货号：14-486

品牌：Merck Millipore

规格：10Ug

目录价：￥6586.00

市场价格：￥5598.10

会员价格：￥5268.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: p70 S6 Kinase (T412E), active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. View All» UniProt Summary: FUNCTION: SwissProt: P23443 # Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.SIZE: 525 amino acids; 59140 Da SUBUNIT: Interacts with PPP1R9A/neurabin-1 (By similarity).SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell junction, synapse, synaptosome (By similarity).TISSUE SPECIFICITY: Widely expressed.SIMILARITY: SwissProt: P23443 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 48.7kDa View All» Brand Family: Upstate View All» Source: expressed in Sf21 cells View All» Protein Target: p70S6K View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: AGC View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• RPS6KB1

• p70-alpha

• p70S6k

• p70-S6K

• p70

• S6K

• S6Kalpha)

• P70S6K

• STK14A

• S6K1

• p70(S6K)-alpha

• PS6K
  View All» Product Name: p70 S6 Kinase (T412E), active View All» Quality Assurance: routinely evaluated by phosphorylation of S6 Kinase/Rsk-2 Substrate Peptide 2 View All» UniProt Number: P23443 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 250μg size as catalog # 14-486M - Call for pricing and availability. View All» Entrez Gene Number: NM_003161.2 View All» Purification Method: Ni²⁺/NTA-agarose View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：https://16ao.com/thread-140905.htm
  © Merck Millipore代理14-486 p70 S6 Kinase Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio