货号：14-339M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Akt2/PKBβ (δPH, S474D), active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: Recombinant human PKBβ, residues 120-481, S474D, containing an N-terminal His6 tag; activated by PDK1. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. View All» UniProt Summary: FUNCTION: SwissProt: P31751 # General protein kinase capable of phosphorylating several known proteins.SIZE: 481 amino acids; 55769 Da TISSUE SPECIFICITY: In all human cell types so far analyzed.DISEASE:SwissProt: P31751 # Alterations of AKT2 may contribute to the pathogenesis of ovarian carcinomas.SIMILARITY: SwissProt: P31751 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 PH domain. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 42.8kDa View All» Brand Family: Upstate View All» Source: Expressed by baculovirus in Sf21 insect cells. View All» Protein Target: Akt2/PKBβ View All» Storage Conditions: 1 year at -70°C View All» Target Sub-Family: AGC View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• AKT2

• RAC-BETA

• PRKBB

• PKBBETA

• RAC-PK-beta
  View All» Product Name: Akt2/PKBβ (δPH, S474D), active View All» Quality Assurance: Routinely evaluated by phosphorylation of Crosstide View All» UniProt Number: P31751 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-339) and in bulk (cat# 14-339-K). View All» Entrez Gene Number: NM_001626.3 View All» Purification Method: Ni²⁺/NTA-agarose & heparin-Sepharose™ chromatography View All»
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  © Merck Millipore代理14-339M Akt2/PKBβ (δPH, S474D) Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio