金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Cripto Long Name: Teratocarcinoma-derived Growth Factor/Cripto Growth Factor Aliases: CFC-2; TDGF1; TDGF-1 Entrez Gene IDs: 6997 (Human); 21667 (Mouse) Background: Cripto Cripto, also known as TDGF-1 (Teratocarcinoma-Derived Growth Factor), is the founding member of the Epidermal Growth Factor-Cripto-1/FRL1/Cryptic Protein family of signaling proteins that function in cancer and various developmental processes. Mouse Cripto shares 66% and 34% amino acid identity with human Cripto and zebrafish one-eyed pinhead (OEP), respectively. Genetic evidence from mice and zebrafish points to a role for Cripto as an essential cofactor in Nodal signaling.