金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: sFRP-1 Long Name: Secreted Frizzled Related Protein 1 Aliases: FrzA; SARP-2 Entrez Gene IDs: 6422 (Human); 20377 (Mouse); 84402 (Rat) Background: Secreted Frizzled Related Proteins (sFRP) Secreted Frizzled related proteins are secreted glycoproteins with homology to the Wnt-binding domain of the Frizzled family of transmembrane receptors. sFRPs contain an N-terminal Frizzled-like cysteine-rich domain (CRD) with 10 conserved cysteines and a C-terminal heparin-binding region. sFRPs function as soluble antagonists of Wnt signaling by binding directly to Wnt proteins and preventing their interactions with Frizzled receptors.