金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CD28 Aliases: CD28 Entrez Gene IDs: 940 (Human); 12487 (Mouse) Background: CD28 CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.