金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IL-7 R alpha/CD127 Long Name: Interleukin 7 Receptor alpha Aliases: CD127; IL7R Entrez Gene IDs: 3575 (Human); 16197 (Mouse) Background: IL-7 R alpha The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c). Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.