金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ala253-Gly366 Accession #:Q07104 N-terminal Sequence Analysis:Ala253 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:13.1 kDa (monomer) Activity:Measured by its ability to bind with Recombinant Human ActivinRIB/ALK‑4 Fc Chimera (Catalog# 808-AR) in the presence of Recombinant Mouse Cripto (Catalog# 1538-CR) in functional ELISA. Chen, et al. (2005) Development 133:319.Immobilized rmGDF-3 at 1 µg/mL (100 µL/well) can bind rhActivin RIB/Fc Chimera with an apparent K_D<100 nM. Formulation:Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.See Certificate of Analysis for details. Molecule Information: GDF-3 Long Name: Growth Differentiation Factor 3 Aliases: Vgr-2 Entrez Gene IDs: 9573 (Human); 14562 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.