金山科研平台，产品价格货期咨询微信：jinshanbio Source:Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ala206-Asp697, Ser, and a C-terminal 10-His tag Accession #:Q61072 N-terminal Sequence Analysis:Ala206 Structure:Mature form. Recombinant Mouse ADAM9 is prone to proteolytic cleavage at C-terminus. The poly-His tag may not be present in the preparation. Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:55 kDa SDS-PAGE:61 kDa, reducing conditions Activity:Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH₂ (Catalog# ES003).The specific activity is >5.0 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl, ZnCl₂, Brij-35 and Glycerol.See Certificate of Analysis for details. Molecule Information: ADAM9 Long Name: A Disintegrin and Metalloprotease-like Domain 9 Aliases: MCMP; MDC9; Meltrin gamma Entrez Gene IDs: 8754 (Human); 11502 (Mouse) Background: ADAMs (A Disintegrin and Metalloprotease) Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.