金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P20334 N-terminal Sequence Analysis:Val24 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:44.3 kDa (monomer) SDS-PAGE:62-66 kDa, reducing conditions Activity:Measured by its ability to bind recombinant mouse 4-1BB Ligand in a functional ELISA.Measured by its ability to block 4-1BBL-induced IL-2 secretion by mouse Tcells.The ED₅₀ for this effect is typically 0.3-1 µg/mL in the presence of 0.4 µg/mL of recombinant mouse 4-1BBL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: 4-1BB/TNFRSF9/CD137 Aliases: CD137; ILA; TNFRSF9 Entrez Gene IDs: 3604 (Human); 21942 (Mouse); 500590 (Rat) Background: 4-1BB/TNFRSF9 (CD137) 4-1BB is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is alternatively known as TNFRSF9, CD137, and ILA. The human and mouse proteins share 60% amino acid sequence identity. 4-1BB is absent from naive T cells, but it is upregulated and continually expressed following T cell activation.