R&D Systems代理912-PL-025 Recombinant Porcine IL-12 Protein (25 UG)-试剂-金山科研平台

R&D Systems代理912-PL-025 Recombinant Porcine IL-12 Protein (25 UG)

2025-06-28

货号：912-PL-025

品牌：R&D Systems

规格：25ug

目录价：￥5040.00

市场价格：￥4032.00

会员价格：￥4032.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:Q28938 (p40) & Q29053 (p35) N-terminal Sequence Analysis:Ile23 (p40) & Arg26 (p35) Structure:Disulfide-linked heterodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. SDS-PAGE:60-70 kDa, non-reducing conditions Activity:Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. Symons, J.A. etal. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etal. (eds): IRL Press. 272.The ED₅₀ for this effect is typically 0.05-0.15ng/mL. Molecule Information: IL-12 Long Name: Interleukin 12 Aliases: CLMF1; IL12A; NKSF1 Entrez Gene IDs: 3592 (Human); 16159 (Mouse); 84405 (Rat); 403977 (Canine); 493741 (Feline) Background: IL-12

View IL-12 IHC images. Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.

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