金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:CAA45177 N-terminal Sequence Analysis:Asp108 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:87.4 kDa SDS-PAGE:120-130 kDa, under reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells.When 1 x 10⁵ cells/well are added to rhP-CAD/Fc Chimera coated plates (10 µg/mL with 100 µL/well), approximately 30 - 60% will adhere after 1.5 hours at 37° C. Optimal concentration depends on cell type as well as the application or research objectives. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: P-Cadherin Long Name: Placental Cadherin Aliases: CAD3; Cadherin-3; CDH3; CDHP; HJMD; PCAD Entrez Gene IDs: 1001 (Human); 12560 (Mouse) Background: Cadherins

The cadherin superfamily comprises a large number of cell surface glycoproteins with one or more cadherin repeats, which are involved in Ca2⁺-dependent cell-cell adhesion. Classical cadherins contain five extracellular cadherin repeats and a conserved cytoplasmic region that interacts with the actin cytoskeleton via catenins. In addition to cell adhesion, cadherins also mediate morphogenesis, cytoskeletal organization, and cell migration. In addition to the classical cadherins, the cadherin superfamily also includes desmosomal cadherins, protocadherins, 7TM cadherins, FAT family cadherins, and T-cadherin.