R&D Systems代理774-M2-200 Recombinant Mouse ICAM-2/CD102 Fc Chimera Protein, CF (200 UG)

2025-06-28

货号:774-M2-200

品牌:R&D Systems

规格:200ug

目录价:¥9270.00

市场价格:¥7416.00

会员价格:¥7416.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P35330 N-terminal Sequence Analysis:Ser20 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:49.5 kDa (monomer) SDS-PAGE:75-80 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.When 5 x 104 cells/well are added to rmICAM-1/Fc Chimera coated plates (12.5 µg/mL with 100 µL/well), approximately 65 - 85% will adhere after 1 hour incubationat37 °C.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in Tris, Citric Acid and NaCl.See Certificate of Analysis for details. Molecule Information: ICAM-2/CD102 Long Name: Intercellular Adhesion Molecule 2 Aliases: CD102 Entrez Gene IDs: 3384 (Human); 15896 (Mouse) Background: ICAM-2/CD102

    View ICAM-2 IHC images. Intercellular adhesion molecule 2 (ICAM-2), also known as CD102, is a member of the immunoglobulin superfamily and binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.

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