金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:P01233 (CG beta ) & P01215 (CG alpha ) N-terminal Sequence Analysis:Ser21 (CG beta ) & Ala25 (CG alpha ) Structure:Noncovalently-linkedheterodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:15.5 kDa (CG beta ) &10.2 kDa(CG alpha ) SDS-PAGE:27-32 kDa & 20-22 kDa, reducing conditions Activity:Measured by its ability to induce cAMP accumulation in MLTC‑1 mouse Leydig tumor cells. Rebois, R.V. et al. (1982) J. Cell Biol. 94:70.The ED₅₀ for this effect is typically 0.07-0.42 ng/mL. Molecule Information: Chorionic Gonadotropin alpha/beta (HCG) Aliases: CGB; CGB3; Choriogonadotropin Entrez Gene IDs: 1082 (Human) Background: HCG HCG is a glycoprotein hormone secreted in pregnancy by embryonic trophoblast cells during the first 7 weeks of gestation. Production subsequently shifts to the placenta, where it continues until term. HCG is a heterodimer consisting of an alpha chain and a beta chain. The alpha chain is common to several other hormones, including lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), while the beta chain is unique to HCG. Both alpha and beta chains contain a cysteine knot motif, also found in growth factors such as TGF-beta family members.