金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Gly13-Ser164 Accession #:Q8R460 N-terminal Sequence Analysis:Gly13 Structure:Monomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:17.3 kDa SDS-PAGE:17 kDa, reducing conditions Activity:Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. Towne, J.E. et al. (2004) J. Biol. Chem. 279:13677.The ED₅₀ for this effect is typically 3 - 18 ng/mL. Molecule Information: IL-36 gamma/IL-1F9 Long Name: Interleukin 36 gamma/Interleukin 1 Family 9 Aliases: IL-1 H1; IL1F9; IL-1rp2; IL36G Entrez Gene IDs: 56300 (Human); 215257 (Mouse); 499744 (Rat) Background: IL-36 gamma Interleukin 36 gamma (IL-36 gamma), also known as IL-1F9 and IL-1H1 is a member of the IL-1 family. IL-36 gamma is secreted when transfected into 293-T cells. Cells reported to express IL-36 gamma include Langerhans cells, keratinocytes/stratified squamos epithelium, chief cells, and parietal cells. The receptor for IL-36 gamma is reported to be a combination of IL-1 R6/IL-1 R rp2 and IL-1 R3/IL-1 R AcP. Recombinant IL-36 gamma has been shown to activate pathways involving NF-kappa B and MAPK in an IL-1 R6/IL-1 R rp2-dependent manner.