金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:O88713 N-terminal Sequence Analysis:Met Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:42.2 kDa (monomer) SDS-PAGE:45-57 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.WhenRecombinant Mouse KLRG1 Fc Chimerais immobilized at5 µg/mL (100µL/well), the concentration ofRecombinant Mouse E-Cadherin Fc Chimera (Catalog# 748-EC)that produces 50% of the optimal binding response is found to be approximately0.1 -0.4µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: KLRG1 Long Name: Killer Cell Lectin-like Receptor Subfamily G Member 1 Aliases: CLEC15A; MAFA; MAFAL Entrez Gene IDs: 10219 (Human); 50928 (Mouse); 58975 (Rat) Background: KLRG1 KLRG1 (killer cell lectin-like receptor G1), also called MAFA (mast cell function associated), is a 30-38 kDa type II transmembrane inhibitory glycoprotein of the C-type lectin family, designated CLEC15A. KLRG1 binds E-, N- and R-cadherins and functions as an MHC-independent means of identifying non-self pathogens and epithelial tumor cells with low E-cadherin expression. It is expressed as a monomer or disulfide-linked homodimer on NK and T cell subsets such as tumor-infiltrating lymphocytes.