金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Met1-Thr607, with a C-terminal 6-His tag Accession #:BAA87415 N-terminal Sequence Analysis:Ser48 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:62.2 kDa SDS-PAGE:80 -90 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of U‑87MG human glioblastoma/astrocytoma cells.

The ED₅₀ for this effect is typically 1.0 - 4.0 µg/mL.

Optimal dilutions should be determined by each laboratory for each application.

The cadherin superfamily comprises a large number of cell surface glycoproteins with one or more cadherin repeats, which are involved in Ca2⁺-dependent cell-cell adhesion. Classical cadherins contain five extracellular cadherin repeats and a conserved cytoplasmic region that interacts with the actin cytoskeleton via catenins. In addition to cell adhesion, cadherins also mediate morphogenesis, cytoskeletal organization, and cell migration. In addition to the classical cadherins, the cadherin superfamily also includes desmosomal cadherins, protocadherins, 7TM cadherins, FAT family cadherins, and T-cadherin.