金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Met1-Gly245 Accession #:P15260 N-terminal Sequence Analysis:Glu18 & Gly20 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:25 kDa SDS-PAGE:40 kDa and 50 kDa, reducing conditions Activity:Measured by its ability to inhibit rhIFN-gamma mediated protection of HeLa human cervical epithelial carcinoma cells to viral lysis. Meager, A. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 129.The ED₅₀ for this effect is typically 1 - 3µg/mL in the presence of 2ng/mL rhIFN-gamma. Molecule Information: IFN-gamma R1/CD119 Long Name: Interferon gamma Receptor 1 Aliases: CD119; IFNGR1 Entrez Gene IDs: 3459 (Human); 15979 (Mouse) Background: IFN-gamma R1/CD119 The high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta). Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.