金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Met1-Asp295 Accession #:Q14749 N-terminal Sequence Analysis:Val2 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. Endotoxin Level: Predicted Molecular Mass:33 kDa SDS-PAGE:31-35 kDa, reducing conditions Activity:Measured by its ability to transfer a methyl group from S-adenosylmethionine to glycine.The specific activity is >190 pmol/min/µg. Formulation:Supplied as a 0.2 µm filtered solution in NaH₂PO₄, NaCl and Glycerol.See Certificate of Analysis for details. Molecule Information: Glycine N-Methyltransferase/GNMT Aliases: GNMT Entrez Gene IDs: 27232 (Human); 14711 (Mouse); 25134 (Rat) Background: Glycine N-methyltransferase Glycine N-methyltransferase (GNMT) is a cytoplasmic homotetramer of 32 kDa units that converts S-adenosylmethionine to N-methylglycine (sarcosine), also producing S-adenosylhomocysteine. It is abundant in liver, but has also been found in the pancreas and prostate, and is downregulated in hepatocellular carcinoma. GNMT adjusts liver methyl group synthesis for dietary methionine, influencing DNA methylation. The 5-methyltetrahydrofolate form of folic acid binds and inhibits GNMT activity.