金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Met1-Glu311, with a C-terminal 6-His tag Accession #:O00204 N-terminal Sequence Analysis:Met1 Purity:>80%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. Endotoxin Level: Predicted Molecular Mass:36 kDa SDS-PAGE:34-37 kDa, reducing conditions Activity:Measured by its ability to transfer sulfate from PAPS to pregnenolone.The specific activity is >10 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol, Brij and DTT.See Certificate of Analysis for details. Molecule Information: Cytosolic Sulfotransferase 2B1/SULT2B1 Aliases: HSST2; SULT2B1 Entrez Gene IDs: 6820 (Human); 54200 (Mouse); 292915 (Rat) Background: Cytosolic Sulfotransferase 2B1 SULT2B1 (Sulfotransferase 2B1; also ST2B1 and alcohol sulfotransferase) is a 45-48 kDa member of the sulfotransferase 1 family of enzymes. SULT2B1 is widely expressed, being found in platelets, stratum granulosum keratinocytes, breast and prostatic epithelium, and syncytiotrophoblast cells. SULT2B1 catalyzes the sulfonation of DHEA, a precursor for sex steroids, and cholesterol, which supports stratification of the epidermis. Human SULT2B1 is 365 amino acids (aa) in length. There are PAPS binding sites between aa 70-75 and 147-155, a myristoylation motif between aa 255-259, and a Pro-rich region between aa 305-364 that may extend enzyme half-life. There is one 43 kDa splice form (ST2B1a) that shows an eight aa substitution for aa 1-23. It is expressed in fetal brain and generates pregnenolone sulfate, a steroid that modulates neurotransmitters. Full-length human SULT2B1 shares 71% aa identity with mouse SULT2B1.