金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gly26-Ile343, with a C-terminal 6-His tag Accession #:Q6PAL1 N-terminal Sequence Analysis:Gly26 Structure:Monomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:36.4 kDa SDS-PAGE:45-60 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When recombinant mouse Draxin is immobilized at 2 µg/mL, recombinant human LRP-6 FcChimera (Catalog# 1505-LR)binds with an apparent K_D < 20 nM. Molecule Information: Draxin Long Name: Dorsal Repulsive Axon Guidance Protein Aliases: C1orf187; Neucrin Entrez Gene IDs: 374946 (Human); 70433 (Mouse); 691317 (Rat) Background: Draxin Draxin (Dorsal repulsive axon guidance protein; also neucrin) is a secreted, 58 kDa, presumable glycoprotein member of the draxin family of repulsive guidance proteins. In mammals, it is expressed in neurons (axons), astroglia, and likely cells of the developing somite. Draxin acts as a Wnt antagonist by binding to LRP6. The net effect is to block neural crest migration, and promote the organization of axons into functional tracts or bundles (fasciculation).