金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ser2-Ala201 Accession #:Q16619 N-terminal Sequence Analysis:Ser2 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:21 kDa Activity:Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.The ED₅₀ for this effect is typically0.25-1.25ng/mL. Molecule Information: Cardiotrophin-1/CT-1 Aliases: CTF1 Entrez Gene IDs: 1489 (Human); 13019 (Mouse) Background: Cardiotrophin-1 Cardiotrophin-1 (CT-1) is a member of a cytokine family that also includes IL-6, IL-11, LIF, OSM, CLC, CT-2/(Np), CNTF, and IL-31. It has overlapping functions with other IL-6 family members on a variety of cell types. Full-length human and mouse CT-1 lack a canonical signal sequence and share 79% amino acid sequence identity. CT-1 is highly expressed in heart, skeletal muscle, liver, lung, and kidney. Lower levels of CT-1 expression are also observed in testis and the brain.