金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:AAY82472 N-terminal Sequence Analysis:Val23 & Glu29 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:59.3 kDa (monomer) SDS-PAGE:85-100 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of HuT78 human cutaneous T cell lymphoma cells.When 5 x 10⁴ cells/well are added torecombinant human MAdCAM-1/Fc Chimeracoated plates (2.5µg/mL with 100µL/well), approximately 50% - 70% will adhere after1 hourincubation at 37 °C in the presence of 1mMMnCl₂.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: MAdCAM-1 Long Name: Mucosal Addressin Cell Adhesion Molecule 1 Entrez Gene IDs: 8174 (Human); 17123 (Mouse) Background: MAdCAM-1 Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an immunoglobulin (Ig) cell adhesion molecule. MAdCAM-1 is involved in lymphocyte homing to mucosal sites and is expressed on high endothelial venules (HEV) of both mesenteric lymph nodes and Peyers patches. It has also been found on sinus-lining cells of the spleen.