金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gly110-Asn638 with a C-terminal 6-His tag Accession #:P16519 N-terminal Sequence Analysis:Gly110 Structure:Monomer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:59 kDa SDS-PAGE:69 kDa, reducing conditions Activity:Measured by its ability to cleave the fluorogenic peptide substrate pERTKR-AMC (Catalog# ES013).The specific activity is >60 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl and CaCl₂.See Certificate of Analysis for details. Molecule Information: Proprotein Convertase 2/PCSK2 Long Name: Proprotein Convertase Subtilisin/Kexin Type 2 Aliases: NEC2; PC2; PCSK2; SPC2 Entrez Gene IDs: 5126 (Human); 18549 (Mouse); 25121 (Rat) Background: Proprotein Convertases This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.