金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Glu2-Leu295 with an N-terminal Met and 6-His tag Accession #:P50224 N-terminal Sequence Analysis:Met Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:35 kDa SDS-PAGE:36 kDa, reducing conditions Activity:Measured by its ability to transfer sulfate from PAPS to 1-Napthol.The specific activity is >150 pmol/min/µg, as measured under the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.See Certificate of Analysis for details. Molecule Information: Cytosolic Sulfotransferase 1A3/SULT1A3 Aliases: HAST; HAST3; M-PST; STM; SULT1A3; TL-PST Entrez Gene IDs: 6818 (Human) Background: Cytosolic Sulfotransferase 1A3 Cytosolic sulfotransferases are a family of Phase II drug-metabolizing enzymes that catalyze the sulfation of many endogenous and xenobiotic substrates. They have important roles in the metabolism of many endogenous compounds including steroids, bile acids, thyroid hormones and monoamine neurotransmitters. They are widely distributed throughout the body and serve to inactivate and increase water-solubility of xenobiotics and therapeutic drugs. They are distinct from Golgi resident sulfotransferases by lacking N-terminal signal-anchor domains and residing only in the cytoplasm. SULT1A3 catalyzes the sulfation of phenolic monoamines, such as dopamine, norepinephrine and serotonin, and phenolic and catecholic drugs. SULT1A3 is also called catecholamine sulfotransferase.