金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:P11627 N-terminal Sequence Analysis:Ile20 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:150.5 kDa (monomer) SDS-PAGE:180‑200 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of Neuro‑2A mouse neuroblastoma cells.When 5 x 10⁴ cells/well are added toRecombinant Mouse L1CAM Fc Chimera coated plates (2.5µg/mL with 100µL/well), approximately40%‑60% will adhereafter50minutesincubation at 37°C.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in MES and NaCl.See Certificate of Analysis for details. Molecule Information: L1CAM Long Name: Cell Adhesion Molecule L1 Aliases: CAML1; CD171; HSAS; HSAS1; MASA; MIC5; NCAM-L1; S10; SPG1 Entrez Gene IDs: 3897 (Human); 16728 (Mouse); 50687 (Rat) Background: L1CAM The cell adhesion molecule L1 (L1CAM) is an immunoglobulin superfamily adhesion molecule that is critical for neural development. Two alternatively spliced isoforms of L1CAM have been described. The full-length signaling isoform is expressed exclusively in neurons. The second non-neuronal variant lacks a five-residue extracellular sequence and a four residue cytoplasmic sequence that is important in signaling and clathrin-mediated endocytosis.