金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Met21005-Gln21992 (His21384Pro, Ser21487Cys, & Leu21691Pro) with a C-terminal 6-His tag Accession #:Q8WXI7 N-terminal Sequence Analysis:Met21102 Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:110 kDa SDS-PAGE:170-200 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When rhMUC-16 is coated at1 µg/mL (100 µL/well), the concentration ofrhGalectin-3 that produces 50% of the optimal binding responseis found to be approximately0.35 - 1.4 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: CA125/MUC16 Long Name: Ovarian Cancer Antigen CA125 Aliases: MUC16 Entrez Gene IDs: 94025 (Human) Background: CA125 The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.