金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:P37176 N-terminal Sequence Analysis:Val29 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:86.8 kDa (monomer) SDS-PAGE:95-105 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When Recombinant Porcine Endoglin/CD105 Fc Chimerais immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse TGF‑beta RI/ALK‑5 Fc Chimera (Catalog# 587-RI) that produces 50% of the optimal binding response is found to be approximately 2-7 µg/mL.Measured by its ability to inhibit BMP-10-induced alkaline phosphatase production by MC3T3‑E1 mouse preosteoblast cells.The ED₅₀ for this effect is typically 0.3-1.2 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Endoglin/CD105 Aliases: CD105; ENG Entrez Gene IDs: 2022 (Human); 13805 (Mouse) Background: Endoglin Endoglin, also known as CD105, is a type I integral transmembrane glycoprotein and is an accessory receptor for TGF-beta superfamily ligands. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages.