R&D Systems代理551-MR-100 Recombinant Mouse IL-15 R alpha Fc Chimera Protein, CF (100 UG)

2025-06-29

货号:551-MR-100

品牌:R&D Systems

规格:100ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q60819 N-terminal Sequence Analysis:Gly33 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:44.9 kDa (monomer) SDS-PAGE:80-90 kDa, 42 kDa and 35 kDa, reducing conditions Activity:Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. Ruchatz,H. etal. (1998) J.Immunol. 160:5654.The ED50 for this effect is typically0.1 - 0.5ng/mL in the presence of0.1ng/mL recombinant human IL-15. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: IL-15 R alpha Long Name: Interleukin 15 Receptor alpha Aliases: CD215; IL15RA Entrez Gene IDs: 3601 (Human); 16169 (Mouse) Background: IL-15 R alpha

    View IL-15 R alpha IHC images. Interleukin 15 receptor alpha (IL-15 R alpha) is a high affinity receptor that specifically binds IL-15 and associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. IL-15 R alpha is expressed on a wide variety of Tand B cells as well as non-lymphoid cells. Human IL-15 R alpha shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

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