金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Gln31-Lys424, with a C-terminal 6-His tag Accession #:Q86VH4 N-terminal Sequence Analysis:No results obtained: Gln31 predicted Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:46.0 kDa SDS-PAGE:60-70 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When rhLRRTM4 is coated at 5 µg/mL (100 µL/well), rhNeurexin 1 beta/Fc Chimera (R&DSystems, Catalog# 5268-NX) binds with an apparent K_D < 15 nM. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: LRRTM4 Long Name: Leucine Rich Repeat Transmembrane Neuronal 4 Entrez Gene IDs: 80059 (Human); 500219 (Rat) Background: LRRTM Family The LRRTM (leucine-rich repeat transmembrane neuronal) family consists of four type I transmembrane glycoproteins within the LRR protein superfamily. All members of this family are type I transmembrane proteins that contain 10 external LRR repeats plus a short cytoplasmic tail that binds PDF motifs. LRRTMs in mouse show distinct expression patterns during formation of the central nervous system and expression persists in adult brain. LRRTM1 polymorphisms are associated paternally with handedness and schizophrenia, while LRRTM3 may be mutated in late-onset Alzheimer’s disease.