金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Pro132-Leu279, with an N-terminal Met and 6-His tag Accession #:Q544E9 N-terminal Sequence Analysis:Met Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:18 kDa (monomer) SDS-PAGE:27-33kDa, reducing conditions Activity:This soluble Recombinant Mouse Fas Ligand/TNFSF6 has weak cytotoxic activity. It has no effects on A20 mouse B cell lymphoma cells which express mouse Fas.This is one of multiple forms available for this protein. Check R&D Systems' website, www.RnDSystems.com, for a complete listing of the products.Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells.The ED₅₀ for this effect is typically 0.25‑1.5 µg/mL in the presence of 10 µg/mL of a cross-linking antibody Mouse Anti-polyHistidine Monoclonal Antibody (Catalog# MAB050). Molecule Information: Fas Ligand/TNFSF6 Aliases: CD178; CD95L; FASLG; TNFSF6 Entrez Gene IDs: 356 (Human); 14103 (Mouse); 25385 (Rat) Background: Fas Ligand/TNFSF6 Fas Ligand is a 40 kDa type II transmembrane protein belonging to the TNF superfamily. The specific receptor for Fas Ligand is Fas (CD95, Apo-1). Fas Ligand is predominantly expressed on activated T cells and natural killer cells, while Fas is expressed on various types of cells. The Fas/Fas Ligand system plays a crucial role in modulating immune responses by inducing cell specific apoptosis. Human Fas Ligand shares 81% sequence identity with mouse Fas Ligand and 78% sequence identity with rat Fas Ligand.