金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q8C4K3 N-terminal Sequence Analysis:Ser22 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:42 kDa (monomer) SDS-PAGE:60-70 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.Immobilized rmGITR/Fc Chimera at 2 µg/mL (100 µL/well) can bind rmGITR Ligand with a linear range of 0.8 - 50 ng/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: GITR/TNFRSF18 Long Name: Glucocorticoid Induced TNF Receptor Family Related Gene Aliases: AITR; CD357; TNFRSF18 Entrez Gene IDs: 8784 (Human); 21936 (Mouse) Background: GITR/TNFRSF18 GITR (glucocorticoid-induced tumor necrosis factor receptor), also named AITR (activation-inducible TNFreceptor superfamily member) and TNFRSF18, is a 228amino acid typeI transmembrane protein belonging to the TNFreceptor superfamily. The GITR cytoplasmic domain has striking similarity to the cytoplasmic domain of 4-1BB and CD27.