金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gly18-Cys682 (pro) & Phe213-Cys682 (mature), both with a C-terminal 10-His tag Accession #:Q8TE58 N-terminal Sequence Analysis:Gly18 & Phe213 Purity:>80%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:74 kDa (pro), 53 kDa (mature) SDS-PAGE:85kDa and65 kDa, reducing conditions Activity:Measured by its ability to cleave Recombinant Human Aggrecan G1-IGD-G2 Domains (Catalog# 1220-PG).Cleavage of 1 µg of rhAggrecan is >90%, as measuredunder the described conditions. Formulation:Supplied as a 0.2 µm filtered solution in MES and NaCl.See Certificate of Analysis for details. Molecule Information: ADAMTS15 Long Name: A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 15 Entrez Gene IDs: 170689 (Human); 235130 (Mouse); 300474 (Rat) Background: ADAMTSs (ADAM metalloprotease with ThromboSpondin type 1 motif) Members of the ADAMTS family contain pro, catalytic, disintegrin-like, cysteine-rich, spacer and a variable number of TS type 1 motifs. In contrast to membrane-anchored ADAMs, ADAMTSs are secreted and are all active proteases. They are essential for aggrecan turnover and procollagen processing, regulation of which is important in many physiological and pathological processes such as angiogenesis and arthritis.