货号：07-790

品牌：Merck Millipore

规格：100UL

目录价：￥6173.00

市场价格：￥5247.05

会员价格：￥4938.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-PKCα (Ser657/Tyr658) Antibody | 07-790 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes phospho-PKCα (Ser657/Tyr658). This sequence is similar to PKCβI (Ser661/Tyr662) and PKCγ (Thr674/Tyr675). View All» Molecular Weight: 82 kDa View All» Immunogen: KLH conjugated peptide corresponding to amino acid region encompassing the human phospho-PKCα (Ser657/Tyr658). View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity:

• Human

• Rat

• Rabbit
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Immunoaffinity purified View All» UniProt Number: P17252 View All» Entrez Gene Number: NM_002737.2 View All» Gene Symbol:
  • PRKCA

  • PKC-A

  • PKCA

  • MGC129901

  • AAG6

  • MGC129900

  • PRKACA

  • PKC-alpha
    View All» Alternate Names: PRKCA, PKC-alpha, PKCA, PRKACA View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. View All» UniProt Summary: FUNCTION: SwissProt: P17252 # PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity).SIZE: 672 amino acids; 76764 Da SUBUNIT: Interacts with CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine.SIMILARITY: SwissProt: P17252 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 C2 domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-PKCα (Ser657/Tyr658) Antibody | 07-790 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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