货号：07-625

品牌：Merck Millipore

规格：200UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ATRIP Antibody | 07-625 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Product Overview: Antibody recognizing ATR-Interacting Protein View All» Specificity: ATRIP View All» Molecular Weight: 85kDa View All» Immunogen: GST fusion protein corresponding to residues 1-181 of human ATR interacting protein (ATRIP) View All» Isotype: IgG View All» Species Reactivity: Human View All» Quality Assurance: Routinely evaluated by immunoblot on modified RIPA lysates from HEK293, HeLa and U20S cells View All» Purification Method: Protein G purfied View All» Presentation: 70% storage buffer (0.05M Tris-glycine, 0.025M sodium phosphate, pH 7.4, 0.15M NaCl, 0.035% sodium azide) and 30% glycerol View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q8WXE1 View All» Entrez Gene Number: AF451323 View All» Gene Symbol:

• ATRIP

• MGC20625

• DKFZp762J2115

• FLJ12343

• AGS1

• MGC21482

• MGC26740
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry
    View All» Entrez Gene Summary: The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: Q8WXE1 # Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.SIZE: 791 amino acids; 85838 Da SUBUNIT: Heterodimer with ATR. The heterodimer binds the RPA complex and is then recruited to single stranded DNA.SUBCELLULAR LOCATION: Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage.TISSUE SPECIFICITY: Ubiquitous.DOMAIN:SwissProt: Q8WXE1 The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.PTM: Phosphorylated by ATR.SIMILARITY: Belongs to the ATRIP family. View All» Brand Family: Upstate View All» Product Name: Anti-ATRIP Antibody | 07-625 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Purified View All» Host: Rabbit View All»
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