Merck Millipore代理07-524 Anti-Spry2 Antibody;store at -20℃

2025-06-28

货号:07-524

品牌:Merck Millipore

规格:200Ug

目录价:¥5053.00

市场价格:¥4295.05

会员价格:¥4042.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Spry2 Antibody | 07-524 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes SPROUTY2. View All» Molecular Weight: 35-40 kDa View All» Immunogen: Peptide corresponding to amino acids 26-39 of human SPROUTY2 View All» Isotype: IgG View All» Species Reactivity:

  • Human

  • Rat

    View All» Control: Positive Control Included: 3T3 Cell Lysate (12-305) View All» Quality Assurance: routinely evaluated by immunoblot in in RIPA lysates from HeLa and 3T3/A31 View All» Purification Method: Protein A purfied View All» Presentation: Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. View All» Storage Conditions: Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: O43597 View All» Entrez Gene Number: NM_005842 View All» Gene Symbol:
    • SPRY2

    • hSPRY2

    • Spry-2

    • MGC23039

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. View All» UniProt Summary: FUNCTION: SwissProt: O43597 # May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.SIZE: 315 amino acids; 34688 Da SUBCELLULAR LOCATION: Cytoplasm. Cell membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).DOMAIN: SwissProt: O43597 The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.SIMILARITY: Belongs to the sprouty family. & Contains 1 SPR (sprouty) domain. View All» Brand Family: Upstate View All» Product Name: Anti-Spry2 Antibody | 07-524 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 μg View All» Format: Purified View All» Host: Rabbit View All»

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