R&D Systems代理4388-MR-050 Recombinant Mouse IL-20 R beta Fc Chimera Protein, CF (50 UG)

2025-06-28

货号:4388-MR-050

品牌:R&D Systems

规格:50ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:NP_001028715 N-terminal Sequence Analysis:Asp14 & Val16 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:49.7 kDa (monomer) SDS-PAGE:62-66 kDa, reducing conditions Activity:Measured by its ability to bind recombinant mouse IL-20 in a functional ELISA with an estimated KD<10nM. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: IL-20 R beta Long Name: Interleukin 20 Receptor beta Aliases: DIRS1; FNDC6; IL-20R2; IL20RB Entrez Gene IDs: 53833 (Human); 213208 (Mouse) Background: IL-20 R beta IL-20 R alpha (or IL-20 R1) and IL-20 R beta (or IL-20 R2) belong to the class II cytokine receptor family. They form multiple heterodimeric signaling complexes that mediate IL-10 family class II cytokine signals. IL-20 R alpha heterodimerizes with IL-20 R beta to form the functional receptor for IL-19, IL-20 and IL-24. IL-20 R alpha also heterodimerizes with IL-10 R beta to form a functional receptor complex for IL-26, while IL-20 R beta heterodimerizes with IL-22 R to form functional IL-20 and IL-24 receptors. The IL-20 receptors are thought to mediate a number of physiological functions including apoptosis, hematopoiesis, and anti-tumor activities.

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